Made in USA · ≥99% HPLC
hGH (176-191) Analog
AOD-9604 10mg
hGH fragment 176-191Tyr-(176-191)C-terminal hGH fragment
A modified C-terminal fragment of human growth hormone (residues 176-191 with an N-terminal tyrosine), supplied as 10 mg sterile lyophilized powder for in-vitro metabolic research.
$89.95
1 in stock
For laboratory and research use only. Not for human consumption.
This product is not a drug, food or cosmetic. It is sold exclusively to qualified researchers and licensed laboratories.
1 in stock
Tested by Freedom Diagnostics TestingHPLC purity + LC-MS identityLot-matched COA on-site
Arrives in 3–5 days
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US-synthesizedMade & lab-released in the United States
Independent COAThird-party Certificate of Analysis per lot
HPLC + LC-MSPurity by HPLC, identity by mass spectrometry
Same-day dispatchOrders before 2 PM CT ship the same business day
What is AOD-9604?
AOD-9604 is a synthetic peptide that models the C-terminal 176–191 domain of human growth hormone (hGH), with an added N-terminal tyrosine. It is studied in lipolysis and adipocyte assays, separately from intact GH, which makes it a fragment tool compound in metabolic research.
Research areas where laboratories buy AOD-9604 for in vitro work include lipolysis and lipid-metabolism assays in adipocyte cell models, comparative studies of GH fragments versus intact growth hormone on metabolic readouts, and IGF-1-independent signaling research. AOD-9604 is not an FDA-approved drug.
Every lot, independently verified
Independently third-party tested and matched to the lot ID printed on your vial. Values below are from the latest released lot.
≥99%
HPLC-UV Purity
Passed full QC panel
Independent third-party lab (Freedom Diagnostics Testing)
View COA (PDF)
Per-lot HPLC-UV + LC-MS · independent third-party lab
Lot details
ProductAOD-9604 10 mg
LotPer-batch on COA
AppearanceWhite lyophilized powder
ReleaseFull QC panel per lot
DocumentationLot-matched COA
Full QC panel · third-party lab6 assays
Purity (HPLC-UV)≥99% per lot ✓
Identity (LC-MS)AOD-9604 ✓
HPLC conformity (2×)Confirmed ✓
Heavy metals (ICP-MS)Not Detected ✓
SterilityNo Growth ✓
Endotoxin (USP <85>)Within limits ✓
Every lot is released against Koi's full QC panel — HPLC purity, LC-MS identity, heavy metals, sterility, and endotoxin — by an independent third-party laboratory (Freedom Diagnostics Testing). The lot-specific certificate is published in our public COA library and matched to the lot ID printed on the vial.
Browse full COA library →
Compound information
Chemical & structural reference data — specifications, molecular profile and handling.
Product Specifications
CompoundAOD-9604 (modified hGH 176–191 fragment)
Vial size10 mg
Purity≥99% by HPLC
Identity confirmationMass spectrometry
FormLyophilized white powder
Appearance in solutionClear, colorless solution
ManufacturingSynthesized and lyophilized in the United States
Quality testingIndependent third-party laboratory release (Freedom Diagnostics Testing)
Molecular Profile
FragmenthGH (176–191) + N-terminal Tyr
Molecular formulaC78H123N23O23S2
Molecular weight1815.08 g/mol
CAS number221231-10-3
OriginC-terminal 176–191 domain of hGH
Structure classModified GH fragment
Storage & Handling
AppearanceWhite lyophilized powder
SolubilitySterile water or buffer · neutral pH
Storage · powder−20 °C, desiccated, dark (−80 °C long-term)
In solution2–8 °C; aliquot & freeze, avoid freeze-thaw
AOD-9604 Mechanism of Action
- Models the C-terminal 176–191 domain of human growth hormone with an added N-terminal tyrosine.
- Studied for effects on lipid metabolism and lipolysis in adipocyte models.
- Studied in adipocyte assays for IGF-1-independent activity, distinguishing it from intact GH in preclinical work.
- Does not engage the GH receptor's growth-promoting / glucose pathways in the same manner as intact GH.
- Used as a fragment tool compound for separating GH's metabolic from its growth-promoting activities.
- Subject of stability and structure-activity studies of GH C-terminal fragments under defined conditions.
AOD-9604 Research Applications
- Lipolysis and lipid-metabolism assays in adipocyte cell models.
- Comparative studies of GH fragments versus intact GH on metabolic readouts.
- IGF-1-independent metabolic-pathway research.
- Adipocyte differentiation models.
- Structure-activity studies of the hGH (176–191) domain.
- Enzymatic-stability characterization of GH fragments.
Why Buy AOD-9604 from Koi Peptides?
- Every batch of Koi AOD-9604 is synthesized and lyophilized in the United States, then released against independent third-party laboratory (Freedom Diagnostics Testing) testing.
- Each lot is tested by HPLC for purity, LC-MS for identity confirmation, and screened for endotoxin before release.
- The lot ID is printed on every vial and ties back to a public COA library, so researchers can verify documentation before they buy and after the vial arrives.
- Orders placed before 2 PM CT ship the same business day, and shipping is free on orders over $200.
References
The laboratory and preclinical research behind AOD-9604 and GH C-terminal fragments — cited for scientific context.
J. Endocrinology
Molecular and biochemical characterization of the lipolytic domain of human growth hormone
Endocrinology
The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism
View all references +
- Ng, F. M., et al. (2000). Molecular and biochemical characterization of the lipolytic domain of human growth hormone. Journal of Endocrinology.
- Heffernan, M. A., et al. (2001). The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism. Endocrinology, 142(12), 5182–5189.
Regulatory Status
Regulatory status — provided for research context.
Regulatory Status
Regulatory status — provided for research context.
FDA Status
AOD-9604 is not an FDA-approved drug for any indication. The research-grade material supplied by Koi Peptides is synthesized for laboratory research only; it is not formulated, packaged or labeled as a drug, food or cosmetic.
Disclaimer
For laboratory and research use only. Not for human consumption. This product is not a drug, food or cosmetic. It is sold exclusively to qualified researchers and licensed laboratories. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Frequently Asked Questions About AOD-9604
What is AOD-9604 used for in research?+
AOD-9604 is a modified C-terminal fragment of human GH (176–191) studied as a tool compound for lipid metabolism and lipolysis in adipocyte models — used separately from intact GH in IGF-1-independent signaling research. It also appears in comparative GH-fragment versus intact-GH studies and structure-activity work on the 176–191 domain.
What purity is Koi's AOD-9604?+
Each lot is released at ≥99% by HPLC with LC-MS-confirmed identity, against third-party testing covering HPLC purity, LC-MS identity, heavy metals, sterility, and endotoxin. The lot-matched COA is published in the public library against the lot number printed on the vial.
How do I prepare an AOD-9604 solution?+
Dissolve in sterile water or a suitable buffer at neutral pH. Add diluent slowly down the vial wall rather than onto the cake, and avoid vortexing. Prepare working dilutions immediately before use, and for sterile cell-culture work filter through a 0.22 µm low-protein-binding filter. Store prepared solutions at 2 to 8 °C, or aliquot and freeze at −20 °C or below.
What is the CAS number for AOD-9604?+
CAS 221231-10-3. It is the hGH (176–191) fragment with an N-terminal tyrosine, molecular formula C78H123N23O23S2 and molecular weight 1815.08 g/mol.
How should AOD-9604 be stored?+
Store the lyophilized powder at −20 °C, desiccated and protected from light; for long-term storage −80 °C is preferred. Once dissolved, store at 2 to 8 °C or aliquot and freeze. Avoid repeated freeze-thaw cycles.
Is AOD-9604 for human use?+
No. AOD-9604 is for laboratory and research use only and is not for human consumption. It is sold exclusively to qualified researchers and licensed laboratories.
Does AOD-9604 come with a Certificate of Analysis?+
Yes. The lot-specific Certificate of Analysis is published in our public COA library and matched to the lot ID printed on the vial, covering HPLC purity, LC-MS identity, heavy metals, sterility, and endotoxin from an independent third-party laboratory (Freedom Diagnostics Testing).
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